| RQP74177 | |
| I. Background | |
| BTLA is a glycoprotein containing immunoglobulin domains, which is expressed on T cells, dormant B cells, macrophages, dendritic cells and a small number of NK cells. | |
| II. Introduction | |
| Expressed gene: | BTLA、SHP2 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+5ug/ml blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
Figure 1. Recombinant BTLA/SHP2 Reporter Cell constitutively expressing BTLA/SHP2. | |
Figure 2. Inhibtion of HVEM Induced SHP2 Recruitment In BTLA/SHP2 Reporter Cells (C11) By Samples With HVEM/U2OS Cells (C7). | |