| RQP74137 | |
| I. Background | |
| CD161 is a C-type lectin-like membrane receptor expressed at high levels on NK, NKT, Th17, Mucosa Associated Invariant T cells (MAITs), non-MAIT CD8+, tissue-resident memory cells (TRMs) , αβ CD4+ T cells and CD8+ T cells . CD161 levels increase when αβ T cells enter tissues. | |
| II. Introduction | |
| Expressed gene: | CD161 |
| Stability: | 32 passages |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
Figure 1. Dose Response of CD161 Blocking Antibody in CD161 Effector Reporter Cells (Clone 8) With CLEC2D aAPC Cells. | |