BTLA Effector Reporter Cell

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RQP74118
I. Background
BTLA is a glycoprotein containing immunoglobulin domains, which is expressed on T cells, dormant B cells, macrophages, dendritic cells and a small number of NK cells.
 
II. Introduction
Expressed gene:BTLA
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):BTLA
Freeze Medium:90% FBS+10% DMSO
Culture Medium: RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin 
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
 
III. Representative Data

Figure 1. Recombinant BTLA Effector  Reporter Cell constitutively expressing BTLA.


Figure 2. Dose Response of BTLA Blocking Antibody in BTLAEffector Reporter Cells (Clone 1) With HVEM/ TCR Activator - CHO Cells.


 

Figure 3. Dose Response of HVEM Blocking Antibody in BTLA Effector Reporter Cells (Clone 1)With HVEM/TCR Activator - CHO Cells.


Figure 4. Dose Response of BTLA Agonist Abs in BTLA Effector Reporter Cells With FCγR aAPC Cells.