| RQP74107 | |
| I. Background | |
| APOE include Lipoprotein Glomerulopathy and Hyperlipoproteinemia, Type Iii. Among its related pathways are Neuroscience and Lipoprotein metabolism. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and signaling receptor binding. | |
| II. Introduction | |
| Host Cell: | CHO |
| Expressed gene: | APOE |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | Apolipoprotein E |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+600ug/ml hygromycin+2ug/ml puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Description of Host Cell Line | |
| Organism: | Cricetulus griseus, hamster, Chinese |
| Tissue: | Ovary |
| Disease: | Hamster Chinese ovary |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| IV. Representative Data | |
Figure 1. Recombinant CHO-cells constitutively expressing APOE and an engineered T cell receptor (TCR) activator. | |
Figure 2. Dose response of LILRB4 Blocking antibody in LILRB4 Effector Reporter Cells(C5) With APOE TCR Activitor CHO Cells, the EC50= 40 ng/ml. | |
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