| Panel-Ref&® gDNA Cocktail Ⅷ Reference Standard | ||||||
| Cat No. | RQP90020 | |||||
| Description | Contains important loci of common genes, involving EGFR/BRAF/PIK3CA/ERBB2/KRAS and other genes | |||||
| Gene | AA change | CDS Change | Cosmic ID | Expected AF | %AF | Chr position (GRCh37) |
| EGFR | E709A | c.2126A>C | COSM13427 | 5.00% | 5.63% | chr7:55241678 |
| EGFR | L747_A750>P | c.2239_2248insTTAAGAGAAG>C | N/A | 5.00% | 4.83% | N/A |
| EGFR | C797S | c.2389T>A | COSM6493937 | 5.00% | 5.82% | chr7:55249091 |
| ERBB2 | G776>VC | c.2326_2327insTGT | N/A | 5.00% | 4.86% | chr17:37880997_37880998 |
| KRAS | Q61R | c.182A>G | COSM552 | 5.00% | 4.37% | chr12:25380276 |
| KRAS | G13D | c.38G>A | COSM532 | 5.00% | 5.28% | chr12:25398281 |
| NRAS | Q61R | c.182A>G | COSM584 | 5.00% | 5.65% | chr1:115256529 |
| AKT1 | E17K | c.49G>A | COSM33765 | 5.00% | 4.38% | chr14:105246551 |
| BRCA2 | p.I2675Dfs*6 | N/A | N/A | 5.00% | 4.25% | N/A |
| RET | KIF5B-RET | N/A | N/A | 5.00% | 4.48% | N/A |
| ABL1 | BCR-ABL1 | N/A | N/A | 5.00% | 5.89% | N/A |
| MDM2 | CNV | N/A | N/A | CN=5 | CN=4.63 | N/A |
| CDK6 | CNV | N/A | N/A | CN=5 | CN=4.47 | N/A |
| Product Information | ||||||
| Intended Use | Research Use Only | |||||
| Unit Size | 1ug/vial * 1 vial | |||||
| Concentration | Download for COA | |||||
| Purity | Download for COA | |||||
| DNA electrophoresis | Download for COA | |||||
| Storage | 4°C | |||||
| Expiry | 36 months from the date of manufacture | |||||
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