RQP10622 | |
| Format | Genomic DNA |
| Description | ESR1, estrogen receptor alpha, modulates response to estrogen and is used as a marker to predict response to endocrine therapy in breast cancer patients. ESR1 fusions are recurrent in breast cancer, and mutations in ESR1 have been associated with decreased response to endocrine therapy in breast cancer. |
| Technical Data | |
| DNA Change | c.1610A>C |
| AA Change | p.Y537S |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | N/A |
| Cosmic ID | COSM1074639 |
| Chr position(GRCh37) | chr6:152419923 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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