PIK3CA p.E545D Reference Standard

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RQP10623
FormatGenomic DNA
DescriptionPIK3CA E545D is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545D results in increased transformation ability in two different cell lines in culture, and therefore, is predicted to lead to a gain of Pik3ca protein function.
  
Technical Data 
DNA Change:c.1635G>T
AA Changep.E545D
Mutation typeSubstitution - Missense
ZygosityHeterozygous
Allelic FrequencyN/A
TranscriptNM_006218.4
Chr position(GRCh37)chr3:178936093
Buffer:Tris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencingCBP10623.jpg
Storage4℃
Expiry36 months from the date of manufacture