| Panel-Ref™ EGFR Cocktail II 5% Reference Standard | |||||
| Cat No. | RQP90006 | ||||
| Format | Genomic DNA | ||||
| Description | Five mutations containing common EGFR mutations are suitable for EGFR-related tests, as quality control products, reference products, etc. | ||||
| Gene | AA Change | CDS Change | Exon | Cosmic ID | AF% |
| EGFR | p.E746_A750delELREA | c.2236_2250del15 GAATTAAGAGAAGCA>- | 19 | COSM6225 | 5% |
| EGFR | p.G719S | c.2155G>A | 18 | COSM6252 | 5% |
| EGFR | p.V769_D770insASV | c.2307_2308ins GCCAGCGTG | 19 | COSM12376 | 5% |
| EGFR | p.C797S | c.2389T>A | 20 | COSM6493937 | 5% |
| EGFR | p.L861Q | c.2582T>A | 21 | COSM6213 | 5% |
| Product Information | |||||
| Intended Use | Research Use Only | ||||
| Unit Size | 1ug | ||||
| Concentration | Download for COA | ||||
| Purity | Download for COA | ||||
| DNA electrophoresis | Download for COA | ||||
| Storage | -20℃ | ||||
| Expiry | 36 months from the date of manufacture | ||||
| The following list is the common mutation sites of EGFR. We can customize the EGFR Panel according to your needs, or customize the sites that are not in it. | |||||
| Gene | AA Change | CDS Change | Exon | Cosmic ID | AF% |
| EGFR | p.C797S | c.2389T>A | 20 | COSM6493937 | 50% |
| EGFR | p.C797S | c.2390G>C | 20 | COSM5945664 | Coming soon |
| EGFR | p.T790M | c.2369C>T | 20 | COSM6240 | 50% |
| EGFR | p.L861Q | c.2582T>A | 21 | COSM6213 | 100% |
| EGFR | p.V769_D770insASV | c.2307_2308ins GCCAGCGTG | 19 | COSM12376 | 100% |
| EGFR | p.E746_A750delELREA | c.2235_2249del15 GGAATTAAGAGAAGC>- | 19 | COSM6223 | 100% |
| EGFR | p.E746_A750delELREA | c.2236_2250del15 GAATTAAGAGAAGCA>- | 19 | COSM6225 | 50% |
| EGFR | p.L747_A750>P | c.2239_2248TTAAGAGAAG>C | 19 | COSM12382 | 100% |
| EGFR | p.G719A | c.2156G>C | 18 | COSM6239 | 100% |
| EGFR | p.G719S | c.2155G>A | 18 | COSM6252 | 33.33% |
| EGFR | p.G719C | c.2155G>T | 18 | COSM6253 | Coming soon |
| EGFR | p.S768I | c.2303G>T | 20 | COSM6241 | 100% |
| EGFR | p.A763_Y764insFQEA | c.2290_2291ins tccaggaagcct | 19 | COSM26720 | 100% |
| EGFR | p.H773 V774insNPH | c.2319_2320ins AACCCCCAC | 20 | COSM12381 | 100% |
| EGFR | p.D770_N771insSVD | c.2311_2312ins GCGTGGACA | 20 | COSM13428 | 100% |
| EGFR | p.L858R | c.2573T>G | 21 | COSM6224 | 50% |
| EGFR | p.L747_P753>S | c.2240_2257del18 TAAGAGAAGCAACATCTC | 19 | COSM12370 | 100% |
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