c-Kit L576P/BaF3

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Detailed introduction

RQP73298
I. Introduction
Cell Line Name：	c-Kit L576P/BaF3
Host Cell:	Ba/F3
Stability:	16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Application:	Anti-proliferation assay and PD assay
Freeze Medium:	90% FBS+10% DMSO
Complete Culture Medium:	RPMI-1640+10%FBS
Mycoplasma Status:	Negative

II.Background
KIT L576P lies within the juxtamembrane domain (exon 11) of the Kit protein (PMID: 17372901). L576P confers a gain of function to Kit, as indicated by constitutive phosphorylation of Kit, and is transforming in cell culture (PMID: 17372901).

III. Representative Data
1. WB of c-Kit L576P/BaF3
2. Sanger of c-Kit L576P/BaF3
3. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of BaF3 c-KIT L576P (C6).