c-Kit Y823D/BaF3

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Detailed introduction

RQP73208
I. Introduction
Cell Line Name：	c-Kit Y823D/BaF3
Host Cell:	Ba/F3
Stability:	16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:	90% FBS+10% DMSO
Complete Culture Medium:	RPMI-1640+10%FBS
Mycoplasma Status:	Negative

II.Background
KIT Y823D lies within the protein kinase domain of the Kit protein (UniProt.org). Y823D confers a gain of function on Kit, as indicated by constitutive phosphorylation of Kit in cultured cells (PMID: 14695343, PMID: 20633291).

III. Representative Data
1.WB of c-Kit Y823D/BaF3
2.Sanger of c-Kit Y823D/BaF3
3. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of BaF3 c-KIT Y823D (C1).