EGFR Del19-C797S/BaF3

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RQP73172
I. Introduction

Cell Line Name:

EGFR Del19-C797S/BaF3

Host Cell:

Ba/F3

Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

 
II.Background

EGFR is widely recognized for its importance in cancer. Amplification and mutations have been shown to be driving events in many cancer types. Its role in non-small cell lung cancer, glioblastoma and basal-like breast cancers has spurred many research and drug development efforts.

 
III. Representative Data

1. WB of EGFR EGFR Del19-C797S/BaF3

 

2. Sanger of EGFR Del19-C797S/BaF3

Figure 2. EGFR Del19-C797S/BaF3 C797S


 Figure 2. EGFR Del19-C797S/BaF3  Del19

3. Anti-proliferation assay

Figure 4. CTG Proliferation Assay of BaF3 EGFR DEL 19/C797S Cells (C1).