| RQP73172 | |
| I. Introduction | |
Cell Line Name: | EGFR Del19-C797S/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
EGFR is widely recognized for its importance in cancer. Amplification and mutations have been shown to be driving events in many cancer types. Its role in non-small cell lung cancer, glioblastoma and basal-like breast cancers has spurred many research and drug development efforts. | |
| III. Representative Data | |
1. WB of EGFR EGFR Del19-C797S/BaF3
| |
2. Sanger of EGFR Del19-C797S/BaF3
Figure 2. EGFR Del19-C797S/BaF3 C797S
Figure 2. EGFR Del19-C797S/BaF3 Del19 | |
3. Anti-proliferation assay
Figure 4. CTG Proliferation Assay of BaF3 EGFR DEL 19/C797S Cells (C1). | |