RQP73172 | |
I. Introduction | |
Cell Line Name: | EGFR Del19-C797S/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
EGFR is widely recognized for its importance in cancer. Amplification and mutations have been shown to be driving events in many cancer types. Its role in non-small cell lung cancer, glioblastoma and basal-like breast cancers has spurred many research and drug development efforts. | |
III. Representative Data | |
1. WB of EGFR EGFR Del19-C797S/BaF3
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2. Sanger of EGFR Del19-C797S/BaF3 Figure 2. EGFR Del19-C797S/BaF3 C797S Figure 2. EGFR Del19-C797S/BaF3 Del19 | |
3. Anti-proliferation assay Figure 4. CTG Proliferation Assay of BaF3 EGFR DEL 19/C797S Cells (C1). |