| RQP71105 | |
| I. Background | |
| GPR120 is a GPCR that responds to long-chain FAs. This receptor was recently shown to be expressed in macrophages, where it is coupled to the β-arrestin pathway. | |
| II. Introduction | |
| Host Cell: | CHO |
| Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | N/A |
| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): | Functional assay for GPR120 receptor |
| Transducer: | Gq/G11 family |
| Ⅲ. Description of Host Cell Line | |
| Organism: | Hamster |
| Tissue: | Ovary |
| Morphology: | Epithelial |
| Growth Properties: | Adherent |
| Ⅳ. Representative Data | |
Figure 1.Dose Response of TUG-891 in GPR120 CHO Cells (C1). | |
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