EDNRA/CHO

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RQP71373
I. Background
EDNRA (Endothelin Receptor Type A) is a Protein Coding gene. Diseases associated with EDNRA include Mandibulofacial Dysostosis With Alopecia and Migraine With Or Without Aura 1. Among its related pathways are Development Endothelin-1/EDNRA transactivation of EGFR and Class A/1 (Rhodopsin-like receptors). Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and endothelin receptor activity. 
 
II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for EDNRA receptor

Transducer:Gq
 
Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

CBP71373.png

Figure 2. Endothelin 1 efffect on CHO-EDNRA clone 6.