| RQP71363 | |
| I. Background | |
C-C chemokine receptor type 1 (CCR8) is a G protein-coupled receptor member of the CC chemokine subfamily of | |
| II. Introduction | |
| Host Cell: | CHO |
| Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | N/A |
| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): | Functional assay for CCR8 receptor |
| Transducer: | Gi |
| Ⅲ. Description of Host Cell Line | |
| Organism: | Hamster |
| Tissue: | Ovary |
| Morphology: | Epithelial |
| Growth Properties: | Adherent |
| Ⅳ. Representative Data | |
Figure 1. Dose response of Human Recombinant CCL1 in CCR8 β-Arrestin/CHO-K1 Cell Line (C6). | |
Figure 2. Inhibition of CCL1-induced Beta-Arrestin Recruitment By CCR8 Blocking Ab in CCR8 Beta-Arrestin CHO-K1 Cells. | |