C-C chemokine receptor type 1 (CCR1) is a G protein-coupled receptor member of the CC chemokine subfamily of
receptors. Following interaction with its specific chemokine ligands, like macrophage inflammatory protein 1 alpha
(MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), and monocyte
chemoattractant protein 3 (MCP-3), it triggers the onset of a process known as chemotaxis. GenScript’s human
CCR1-expressing stable subline is guaranteed to function properly in the calcium flux assay.

CHO

Functional assay for CCR1 receptor

Figure 2. CCL3 effect on CCR1/CHO-K1 clone 6.